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Inventi Impact: Ethnopharmacology

Articles

  • Inventi:pep/29324/19
    Investigation of Efficacy Enhancing and Toxicity Reducing Mechanism of Combination of Aconiti Lateralis Radix Praeparata and Paeoniae Radix Alba in Adjuvant-Induced Arthritis Rats by Metabolomics
    Research 2019 : July - September
    Yun-fei Xie, Wu-wen Feng, Mei-chen Liu, Jun Xie, Lei Yu, Xiao-hong Gong, Yun-xia Li, Cheng Peng

    Combination of Aconiti Lateralis Radix Praeparata (FZ) and Paeoniae Radix Alba (BS) shows a significant effect in rheumatoid\narthritis (RA). This study aimed to investigate the efficacy enhancing and toxicity reducing mechanism of combination of them\nin adjuvant-induced arthritis (AIA) rats by metabolomics. Rats were randomly divided into seven groups, including A (healthy\ncontrol), B (model control), C1 (therapy group), C2 (efficacy enhancing group), D1 (toxicity group), and D2 (toxicity reducing\ngroup), and dexamethasone group was used as positive control. The plasma biochemical indexes showed that therapeutic dose of\nlipid-soluble alkaloids of FZ could significantly inhibit the concentrations.....................

    How to Cite this Article
    Attribution/ CC Compliant Citation: Xie, Yun-fei, et al; Investigation of Efficacy Enhancing and Toxicity Reducing Mechanism of Combination\nof Aconiti Lateralis Radix Praeparata and Paeoniae Radix Alba in Adjuvant-Induced Arthritis Rats by Metabolomics; Evidence-Based\nComplementary and Alternative Medicine 2019 (2019).\nhttps://doi.org/10.1155/2019/9864841\nhttp://creativecommons.org/licenses/by/4.0/\n\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article
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